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New England Patriots at Buffalo Bills

NFLWeek 4 • regular • 2026
Scheduled
Bills logo
Bills
Buffalo
0
vs
Patriots logo
Patriots
New England
0
BUF 68%32% NE
Prediction Confidence:
Moderate

Buffalo Bills 68% to win. The top 3 signals favoring Bills:

  • Injuries. Bills healthier: 8 out, 0 doubtful vs Patriots 9 out, 0 doubtful
  • Home Field Advantage. Bills are 2-0 at home this season; Patriots are 0-2 on the road (divisional game, reduced advantage)
  • ELO Rating. Bills ELO 1631 vs Patriots ELO 1585 (diff: +46)

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VenueHighmark Stadium
Orchard Park, NY

Team Comparison

Head-to-head snapshot based on our model inputs

Patriots (away)
Bills (home)
32%
Win probability
68%
0
High-impact factors
1
9
Players ruled out
8

Game Preview

Patriots at Bills

The Patriots visit the Bills at Highmark Stadium in Orchard Park, NY in NFL regular season Week 4 action.

Our model gives the Bills a 68% chance of winning, giving them a clear but not overwhelming advantage. The Patriots will need to find an edge to pull off the upset.

Key factors driving this prediction:

  • Injuries favors the Bills (medium): Bills healthier: 8 out, 0 doubtful vs Patriots 9 out, 0 doubtful
  • Home Field Advantage favors the Bills (high): Bills are 2-0 at home this season; Patriots are 0-2 on the road (divisional game, reduced advantage)
  • ELO Rating favors the Bills (low): Bills ELO 1631 vs Patriots ELO 1585 (diff: +46)
  • Both teams are dealing with injuries -- the Bills have 8 player(s) ruled out, while the Patriots have 9.
Bills68%

is strongly favored to win

Key Factor
Injuries
Favors BUF

Key Factors

What's driving the win probability for this game

  • InjuriesFavors Buffalo Bills
  • Home Field AdvantageFavors Buffalo Bills
  • ELO RatingFavors Buffalo Bills
  • Head to HeadNeutral
  • Rest DaysNeutral
  • Weather ImpactNeutral
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What's Driving This Game

Each factor's contribution to the final win probability

NE
BUF
Injuries
Home Field Advantage
ELO Rating
Favours NE|Favours BUF

Premium feature: factor breakdown

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Model vs. Market

Comparing our probability model against Vegas odds

Bills

Our Model68%

Patriots

Our Model32%

Understanding the win probability calculation

Home Field Advantage

Bills are 2-0 at home this season; Patriots are 0-2 on the road (divisional game, reduced advantage)

Bills

2 factors not shown (insufficient data)

Model version: 1.1.0 • Calculated: 10/4/2026, 4:45:03 PM

Bills

Christian BenfordCB(Toe)
OUT
Jordan HancockCB(Hamstring)
OUT
Mike DannaDE(Coach's Decision)
OUT
T.J. SandersDT
OUT
Ar'maj Reed-AdamsG(Coach's Decision)
OUT
Jude BowryOT(Coach's Decision)
OUT
Jalon KilgoreS(Coach's Decision)
OUT
Skyler BellWR(Coach's Decision)
OUT

Patriots

Christian GonzalezCB(Shoulder)
OUT
Channing CanadaCB(Hamstring)
OUT
Christian BarmoreDT(Shoulder)
OUT
Greg Van RotenG(Thigh)
OUT
Quintayvious HutchinsLB(Knee)
OUT
Dametrious CrownoverOT(Coach's Decision)
OUT
Behren MortonQB(Coach's Decision)
OUT
Tanner ArkinTE(Coach's Decision)
OUT
A.J. BrownWR(Ankle)
OUT

Key Players

Patriots

Behren MortonQBOUT
-7.1% win prob impact
Drake MayeQB
Tommy DeVitoQB
Kobe PrenticeWR
Efton Chism IIIWR

Bills

Josh AllenQB
Kyle AllenQB
Shane BuecheleQB
DJ MooreWR
Ja'Mori MaclinWR

Frequently Asked Questions

Bills has a 68% win probability, while Patriots has a 32% win probability based on our analysis.

Our model considers weather conditions, offensive and defensive efficiency, rest days, injury impact, and historical performance.

This game is being played at Highmark Stadium in Orchard Park, NY.

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